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Dopamine agonist use and the risk of heart failure.

Generic drugs are the same drug products as brand, but they are produced and distributed without patent protection.

Although not reported with pramipexole in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy.

The contents of generic pills are absolutely the same as in the branded versions.

Deep brain stimulation for Parkinson's disease: patient selection and evaluation.

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These findings are thought to be due to the prolactin-lowering effect of pramipexole, since prolactin is necessary for implantation and maintenance of early pregnancy in rats (but not rabbits or humans).

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People with restless legs syndrome -- now also known as Willis-Ekbom disease -- feel throbbing, creeping or other unpleasant sensations in the legs and an uncontrollable urge to move them.

It is important to keep in mind that generic and brand-name drugs do look more or less different.

Dopamine triggers numerous nerve impulses that affect muscle movement.

Study 2 was a randomized-withdrawal study, designed to demonstrate the sustained efficacy of pramipexole for treatment of RLS after a period of six months.

Any levodopa drug should not be used daily because of a very high risk of augmentation.

Generic drugs manufacturers do not need to spend huge amounts on scientific research and development, on extensive clinical trials and marketing campaigns.

A huge part of a brand drug price consists of research and development costs, and advertising.

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