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Very helpful for MS. Helps with leg spasticity and speech problems.

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Spasticity of Cerebral Origin Patients: The clinical goal is to maintain muscle tone as close to normal as possible and to minimize the frequency and severity of spasms to the extent possible, without inducing intolerable side effects, or to titrate the dose to the desired degree of muscle tone for optimal functions.

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Spasticity due to traumatic brain injury: wait at least one year after injury before considering Gablofen therapy.

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Spasticity occurs in up to 78% of people with SCI, and 49% or more require treatment of some kind.

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Chung and Cheng (2010) used an RCT design to determine how the application of transcutaneous electrical nerve stimulation (TENS) would affect lower extremity (LE) spasticity in persons with acute or chronic, complete or incomplete American Spinal Injury Association Impairment Scale (AIS) A, B, C, D, tetraplegia or paraplegia.

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Since cough did not relapse with the minimum dose of 20 mg daily, baclofen was stopped two months later.

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