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04.09.2016, 00:50
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My sister is a Parkinsonism sufferer. Her disease is progressive and she needs really good care, a lot of attention and effective medications to support her organism. Sometimes she literally can't move any part of her body and that scares me to death as I don't know if this will come to an end or she'll stay motionless. Sinemet helps me cope with her symptoms reducing trembling, tremor and avoiding these attacks of paralysis. I hope this drug will show off its full potential soon.


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My sister is a Parkinsonism sufferer. Her disease is progressive and she needs really good care, a lot of attention and effective medications to support her organism. Sometimes she literally can't move any part of her body and that scares me to death as I don't know if this will come to an end or she'll stay motionless. Sinemet helps me cope with her symptoms reducing trembling, tremor and avoiding these attacks of paralysis. I hope this drug will show off its full potential soon.

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Combined uneasiness, twitching, aching, or agitation that occurs in the legs after going to bed, frequently leading to insomnia, which may be relieved temporarily by walking about.

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Patients underwent a single-blind placebo run-in period lasting seven days to demonstrate at least 80 percent compliance with taking study medication.

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The interval between doses of Sinemet CR should be 4-8 hours during the waking day.

Unfortunately, a human double-blind study of 499 patients with moderate or severe head injury failed to show benefit; the magnesium-treated patients actually did worse.

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Because patients with SAD also must fulfill criteria for depression, several randomized trials have assessed the use of antidepressants for this condition.

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Although it is effective against RLS, levodopa may also causes a worsening of symptoms during the afternoon or early evening in 50-80% of patients.

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The patient would like to have some relief from the rigidity and resting tremors she experiences, and the resultant pain in her back, neck, head, left upper thoracic and shoulder area, left hand and foot, and occasionally left leg.

Patients who do not respond clinically to LCIG during the test period will remain on oral therapy.

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After that his original doctor also added Zoloft at 100mg per day and several other medications.

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Your blood pressure will need to be checked often.

Well, on the followup appointment the doc now is giving him the Controlled Release Sinemet to take at night so he will feel smooth until morning and not experience such a big "off" I guess you could say.

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Most patients have been adequately treated with doses of Sinemet CR that provide 400 to 1600 mg of levodopa per day, administered as divided doses at intervals ranging from 4 to 8 hours during the waking day.

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Starting in late 2009 and continuing into 2011 Merck stopped manufacturing the drug while awaiting regulatory approvals due to a change in the supplier of the active ingredient.

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