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It has been 5 days into my dose of Minivelle. My hot flashes reduced drastically, however, the very next day I developed severe arthritis in my knees. It took me until today to realize this could be a side effect. After reading- it is. I have discontinued the patch and hopefully my knees will get better.

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I started on the patch because of menopause (at age 36, no medical reason i.e. surgery). I used the patch for about 6 weeks and had to stop because of a rash at the application site. This was no surprise because band-aids give me rashes too. I had no problem with 0.5 but when moved up to 0.75 I started with the rash.

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